New to Sandboxie

[Unknown_User_403]

Just a few general questions. I have downloaded but not yet installed the free version of Sandboxie v.2.42.

1) Can Sandboxie be configured so that installed programs such as Anti-virus, Anti-spyware etc programs that do automatic updates operate outside of Sandboxie??

2) I frequently try new programs which after trial I wish to remove. When deleting the contents of Sandboxie, do all the program parts and registry entries get deleted??

Thank you