should recreate what is happening:
Run a sandboxed regedit and delete the following key:
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Internet Settings\ZoneMap\Domains
This will delete all your IE trusted/untrusted sites. Now recreate the domains key by adding new, you will now see that all the original trusted/untrusted sites are reloaded as if the sandbox copied them from the original registry. Now add a trusted site to your unsandboxed registry, delete the Domains key in the sandboxed registry, create the Domains key in the Sandboxed registry, now you will see all the sites are back including the new one

What I am trying to do is clear all trusted/untrusted sites by using AutoExec=regedit /s test.reg when IE is sandboxed. The only way to clear these sites in one shot is to delete the Domains key and recreate the Domains key in the reg file, but it appears that recreating the Domains key causes sandboxie to read in the unsandboxed registry which just populates all the sites again. I was hoping that since sandboxie through AutoExec deleted the sandboxed key it would have separated itself from the unsandboxed registry. I know I can use ClosedKeyPath but this just totally blocks the sandboxed IE from doing anything with site settings. Is there a way to have sandboxie load a key into the sandbox so it can be manipulated without rereading the key from the unsandbox registry?
thanks