I have sandboxie 5.16 on Windows 10, and bitdefender Antivirus 2017.
My Firefox v50.1.0 is sandboxed.
But if I enabled the plugin "Wallet" of bitdefender i have the error "SBIE2335 Initialization failed for process bdwtxcr.exe [33 / 5]" each 5 sec.
SO it' s impossible to use Wallet with sandobixe.

Problem number 2 :
when you close the sandboxe, it's impossible to close bdwtxcr.exe in the sandboxie.
So the sandboxe is always enable. I have to reboot my pc to resolve the problem.
note: it's impossible to kill the process too (with firefox leader or not)
For information, the monitoring is:
(Drive) \Device\HarddiskVolume3
(Drive) \Device\HarddiskVolume4
Clsid -------------------------------
File/Key -------------------------------
Image -------------------------------
Ipc -------------------------------
Ipc \RPC Control\epmapper
Ipc \Sessions\1\BaseNamedObjects\SBIE_BOXED_DummyEvent_10732
Ipc \Sessions\1\BaseNamedObjects\SBIE_BOXED_DummyEvent_6876
Ipc \Sessions\1\BaseNamedObjects\SBIE_BOXED_DummyEvent_9836
Ipc \Sessions\1\BaseNamedObjects\SBIE_BOXED_ServiceInitComplete_DcomLaunch
Ipc \Sessions\1\BaseNamedObjects\SBIE_BOXED_ServiceInitComplete_RpcSs
Ipc \Sessions\1\BaseNamedObjects\SboxSession
Ipc O \KnownDlls\advapi32.dll
Ipc O \KnownDlls\bcryptPrimitives.dll
Ipc O \KnownDlls\combase.dll
Ipc O \KnownDlls\CRYPT32.dll
Ipc O \KnownDlls\gdi32.dll
Ipc O \KnownDlls\gdi32full.dll
Ipc O \KnownDlls\IMM32.dll
Ipc O \KnownDlls\kernel.appcore.dll
Ipc O \KnownDlls\kernel32.dll
Ipc O \KnownDlls\KERNELBASE.dll
Ipc O \KnownDlls\MSASN1.dll
Ipc O \KnownDlls\MSVCRT.dll
Ipc O \KnownDlls\PSAPI.DLL
Ipc O \KnownDlls\rpcrt4.dll
Ipc O \KnownDlls\sechost.dll
Ipc O \KnownDlls\shcore.dll
Ipc O \KnownDlls\ucrtbase.dll
Ipc O \KnownDlls\user32.dll
Ipc O \KnownDlls\win32u.dll
Ipc O \KnownDlls\WINTRUST.dll
Ipc O \RPC Control\DNSResolver
Ipc O \RPC Control\lsasspirpc
Ipc O \RPC Control\SbieSvcPort
Ipc O \Security\LSA_AUTHENTICATION_INITIALIZED
Ipc O \Sessions\1\Windows\ApiPort
Ipc O \Sessions\1\Windows\SharedSection
Ipc O \ThemeApiPort
Pipe -------------------------------
Pipe \Device\CNG
Pipe \Device\KsecDD
Pipe O \Device\Afd
WinCls -------------------------------
WinCls X Progman